The within-host population dynamics of Mycobacterium tuberculosis vary with treatment efficacy

BACKGROUND: Combination therapy is one of the most effective tools for limiting the emergence of drug resistance in pathogens. Despite the widespread adoption of combination therapy across diseases, drug resistance rates continue to rise, leading to failing treatment regimens. The mechanisms underly...

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Publicado en:Genome Biol
Autores principales: Trauner, Andrej, Liu, Qingyun, Via, Laura E., Liu, Xin, Ruan, Xianglin, Liang, Lili, Shi, Huimin, Chen, Ying, Wang, Ziling, Liang, Ruixia, Zhang, Wei, Wei, Wang, Gao, Jingcai, Sun, Gang, Brites, Daniela, England, Kathleen, Zhang, Guolong, Gagneux, Sebastien, Barry, Clifton E., Gao, Qian
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395877/
https://ncbi.nlm.nih.gov/pubmed/28424085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1196-0
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