The within-host population dynamics of Mycobacterium tuberculosis vary with treatment efficacy

BACKGROUND: Combination therapy is one of the most effective tools for limiting the emergence of drug resistance in pathogens. Despite the widespread adoption of combination therapy across diseases, drug resistance rates continue to rise, leading to failing treatment regimens. The mechanisms underly...

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Dettagli Bibliografici
Pubblicato in:Genome Biol
Autori principali: Trauner, Andrej, Liu, Qingyun, Via, Laura E., Liu, Xin, Ruan, Xianglin, Liang, Lili, Shi, Huimin, Chen, Ying, Wang, Ziling, Liang, Ruixia, Zhang, Wei, Wei, Wang, Gao, Jingcai, Sun, Gang, Brites, Daniela, England, Kathleen, Zhang, Guolong, Gagneux, Sebastien, Barry, Clifton E., Gao, Qian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395877/
https://ncbi.nlm.nih.gov/pubmed/28424085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1196-0
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