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The within-host population dynamics of Mycobacterium tuberculosis vary with treatment efficacy

BACKGROUND: Combination therapy is one of the most effective tools for limiting the emergence of drug resistance in pathogens. Despite the widespread adoption of combination therapy across diseases, drug resistance rates continue to rise, leading to failing treatment regimens. The mechanisms underly...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Trauner, Andrej, Liu, Qingyun, Via, Laura E., Liu, Xin, Ruan, Xianglin, Liang, Lili, Shi, Huimin, Chen, Ying, Wang, Ziling, Liang, Ruixia, Zhang, Wei, Wei, Wang, Gao, Jingcai, Sun, Gang, Brites, Daniela, England, Kathleen, Zhang, Guolong, Gagneux, Sebastien, Barry, Clifton E., Gao, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395877/
https://ncbi.nlm.nih.gov/pubmed/28424085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1196-0
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