Exosomes and the Prion Protein: More than One Truth

Exosomes are involved in the progression of neurodegenerative diseases. The cellular prion protein (PrP(C)) is highly expressed on exosomes. In neurodegenerative diseases, PrP(C) has at least two functions: It is the substrate for the generation of pathological prion protein (PrP(Sc)), a key player...

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Vydáno v:Front Neurosci
Hlavní autoři: Hartmann, Alexander, Muth, Christiane, Dabrowski, Oliver, Krasemann, Susanne, Glatzel, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395619/
https://ncbi.nlm.nih.gov/pubmed/28469550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00194
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