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Exosomes and the Prion Protein: More than One Truth

Exosomes are involved in the progression of neurodegenerative diseases. The cellular prion protein (PrP(C)) is highly expressed on exosomes. In neurodegenerative diseases, PrP(C) has at least two functions: It is the substrate for the generation of pathological prion protein (PrP(Sc)), a key player...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Hartmann, Alexander, Muth, Christiane, Dabrowski, Oliver, Krasemann, Susanne, Glatzel, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395619/
https://ncbi.nlm.nih.gov/pubmed/28469550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00194
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