TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin

Resolution and formation of facultative heterochromatin is essential to development, reprogramming, and oncogenesis. The mechanisms underlying these changes are poorly understood due to the inability to study heterochromatin dynamics and structure in vivo. We devised an in vivo approach to investiga...

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Veröffentlicht in:Nat Struct Mol Biol
Hauptverfasser: Miller, Erik L., Hargreaves, Diana C., Kadoch, Cigall, Chang, Chiung-Ying, Calarco, Joseph P., Hodges, Courtney, Buenrostro, Jason D., Cui, Kairong, Greenleaf, William J., Zhao, Keji, Crabtree, Gerald R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395302/
https://ncbi.nlm.nih.gov/pubmed/28250416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3384
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