MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice

BACKGROUND: By the time clinical symptoms of Alzheimer’s disease (AD) manifest in patients there is already substantial tau pathology in the brain. Recent evidence also suggests that tau pathology can become self-propagating, further accelerating disease progression. Over the last decade several gro...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Vaccine
Autors principals: Davtyan, Hayk, Chen, Wesley W., Zagorsky, Karen, Davis, Joy, Petrushina, Irina, Kazarian, Konstantin, Cribbs, David H., Agadjanyan, Michael G., Blurton-Jones, Mathew, Ghochikyan, Anahit
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395280/
https://ncbi.nlm.nih.gov/pubmed/28320590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.03.020
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars