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Efferocytosis is impaired in Gaucher macrophages
Gaucher disease, the inherited deficiency of lysosomal glucocerebrosidase, is characterized by the presence of glucosylceramide-laden macrophages resulting from impaired digestion of aged erythrocytes or apoptotic leukocytes. Studies of macrophages from patients with type 1 Gaucher disease with geno...
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| Pubblicato in: | Haematologica |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Ferrata Storti Foundation
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5395106/ https://ncbi.nlm.nih.gov/pubmed/28011901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.155093 |
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