ErbB4-Neuregulin Signaling Modulates Synapse Development and Dendritic Arborization through Distinct Mechanisms

Perturbations in neuregulin-1 (NRG1)/ErbB4 function have been associated with schizophrenia. Affected patients exhibit altered levels of these proteins and display hypofunction of glutamatergic synapses as well as altered neuronal circuitry. However, the role of NRG1/ErbB4 in regulating synapse matu...

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Udgivet i:J Biol Chem
Main Authors: Krivosheya, Daria, Tapia, Lucia, Levinson, Joshua N., Huang, Kun, Kang, Yunhee, Hines, Rochelle, Ting, Annie K., Craig, Ann Marie, Mei, Lin, Bamji, Shernaz X., El-Husseini, Alaa
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395083/
https://ncbi.nlm.nih.gov/pubmed/18819924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800073200
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