ErbB4-Neuregulin Signaling Modulates Synapse Development and Dendritic Arborization through Distinct Mechanisms

Perturbations in neuregulin-1 (NRG1)/ErbB4 function have been associated with schizophrenia. Affected patients exhibit altered levels of these proteins and display hypofunction of glutamatergic synapses as well as altered neuronal circuitry. However, the role of NRG1/ErbB4 in regulating synapse matu...

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Pubblicato in:J Biol Chem
Autori principali: Krivosheya, Daria, Tapia, Lucia, Levinson, Joshua N., Huang, Kun, Kang, Yunhee, Hines, Rochelle, Ting, Annie K., Craig, Ann Marie, Mei, Lin, Bamji, Shernaz X., El-Husseini, Alaa
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395083/
https://ncbi.nlm.nih.gov/pubmed/18819924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800073200
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