ErbB4-Neuregulin Signaling Modulates Synapse Development and Dendritic Arborization through Distinct Mechanisms

Perturbations in neuregulin-1 (NRG1)/ErbB4 function have been associated with schizophrenia. Affected patients exhibit altered levels of these proteins and display hypofunction of glutamatergic synapses as well as altered neuronal circuitry. However, the role of NRG1/ErbB4 in regulating synapse matu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Krivosheya, Daria, Tapia, Lucia, Levinson, Joshua N., Huang, Kun, Kang, Yunhee, Hines, Rochelle, Ting, Annie K., Craig, Ann Marie, Mei, Lin, Bamji, Shernaz X., El-Husseini, Alaa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395083/
https://ncbi.nlm.nih.gov/pubmed/18819924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800073200
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