ErbB4-Neuregulin Signaling Modulates Synapse Development and Dendritic Arborization through Distinct Mechanisms

Perturbations in neuregulin-1 (NRG1)/ErbB4 function have been associated with schizophrenia. Affected patients exhibit altered levels of these proteins and display hypofunction of glutamatergic synapses as well as altered neuronal circuitry. However, the role of NRG1/ErbB4 in regulating synapse matu...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Krivosheya, Daria, Tapia, Lucia, Levinson, Joshua N., Huang, Kun, Kang, Yunhee, Hines, Rochelle, Ting, Annie K., Craig, Ann Marie, Mei, Lin, Bamji, Shernaz X., El-Husseini, Alaa
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395083/
https://ncbi.nlm.nih.gov/pubmed/18819924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800073200
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