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Binding mode analyses of NAP derivatives as mu opioid receptor selective ligands through docking studies and molecular dynamics simulation

Mu opioid receptor selective antagonists are highly desirable because of their utility as pharmacological probes for receptor characterization and functional studies. Furthermore, the mu opioid receptors act as an important target in drug abuse and addiction treatment. Previously, we reported NAP as...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Wang, Huiqun, Zaidi, Saheem A., Zhang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395045/
https://ncbi.nlm.nih.gov/pubmed/28302509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.03.005
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