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PiggyBac Transposon-Mediated Mutagenesis in Rats Reveals a Crucial Role of Bbx in Growth and Male Fertility

Bobby sox homolog (Bbx) is an evolutionally conserved gene, but its biological function remains elusive. Here, we characterized defects of Bbx mutant rats that were created by PiggyBac-mediated insertional mutagenesis. Smaller body size and male infertility were the two major phenotypes of homozygou...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biol Reprod
Päätekijät: Wang, Chieh-Ying, Tang, Ming-Chu, Chang, Wen-Chi, Furushima, Kenryo, Jang, Chuan-Wei, Behringer, Richard R, Chen, Chun-Ming
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for the Study of Reproduction, Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394979/
https://ncbi.nlm.nih.gov/pubmed/27465138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.116.141739
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