CEBPA–double-mutated acute myeloid leukemia displays a unique phenotypic profile: a reliable screening method and insight into biological features

Mutations in CCAAT/enhancer binding protein α (CEBPA) occur in 5–10% of cases of acute myeloid leukemia. CEBPA-double-mutated cases usually bear biallelic N- and C-terminal mutations and are associated with a favorable clinical outcome. Identification of CEBPA mutants is challenging because of the v...

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Publicado no:Haematologica
Main Authors: Mannelli, Francesco, Ponziani, Vanessa, Bencini, Sara, Bonetti, Maria Ida, Benelli, Matteo, Cutini, Ilaria, Gianfaldoni, Giacomo, Scappini, Barbara, Pancani, Fabiana, Piccini, Matteo, Rondelli, Tommaso, Caporale, Roberto, Gelli, Anna Maria Grazia, Peruzzi, Benedetta, Chiarini, Marco, Borlenghi, Erika, Spinelli, Orietta, Giupponi, Damiano, Zanghì, Pamela, Bassan, Renato, Rambaldi, Alessandro, Rossi, Giuseppe, Bosi, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394975/
https://ncbi.nlm.nih.gov/pubmed/28250006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.151910
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