Early reduction of WT1 transcripts during induction chemotherapy predicts for longer disease free and overall survival in acute myeloid leukemia

We investigated the prognostic significance of early peripheral blast clearance as assessed by WT1 transcript reduction during the first days of standard induction therapy in 57 adult patients with acute myeloid leukemia (AML). Quantification of WT1 transcript by real-time quantitative PCR in periph...

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Detalhes bibliográficos
Main Authors: Gianfaldoni, Giacomo, Mannelli, Francesco, Ponziani, Vanessa, Longo, Giovanni, Bencini, Sara, Bosi, Alberto, Vannucchi, Alessandro M.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864391/
https://ncbi.nlm.nih.gov/pubmed/20107153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.011908
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