Early reduction of WT1 transcripts during induction chemotherapy predicts for longer disease free and overall survival in acute myeloid leukemia

We investigated the prognostic significance of early peripheral blast clearance as assessed by WT1 transcript reduction during the first days of standard induction therapy in 57 adult patients with acute myeloid leukemia (AML). Quantification of WT1 transcript by real-time quantitative PCR in periph...

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Bibliografske podrobnosti
Main Authors: Gianfaldoni, Giacomo, Mannelli, Francesco, Ponziani, Vanessa, Longo, Giovanni, Bencini, Sara, Bosi, Alberto, Vannucchi, Alessandro M.
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2010
Teme:
Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864391/
https://ncbi.nlm.nih.gov/pubmed/20107153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.011908
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