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N(2)-Substituted 2′-Deoxyguanosine Triphosphate Derivatives, Selective Substrates for Human DNA Polymerase κ
N(2)-Alkyl-2′-deoxyguanosine triphosphate (N(2)-alkyl-dGTP) derivatives with methyl, butyl, benzyl, 4-ethynylbenzyl substituents were prepared and tested for substrates for human DNA polymerases. N(2)-Benzyl-dGTP was equal to dGTP as a substrate for DNA polymerase κ, but was a poor substrate for pol...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5394382/ https://ncbi.nlm.nih.gov/pubmed/28140505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201611607 |
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