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Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ

Low-density lipoprotein receptor-related protein 1 (LRP1) regulates lipid and glucose metabolism in liver and adipose tissue. It is also involved in central nervous system regulation of food intake and leptin signalling. Here we demonstrate that endothelial Lrp1 regulates systemic energy homeostasis...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Mao, Hua, Lockyer, Pamela, Li, Luge, Ballantyne, Christie M., Patterson, Cam, Xie, Liang, Pi, Xinchun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394236/
https://ncbi.nlm.nih.gov/pubmed/28393867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14960
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