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Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ

Low-density lipoprotein receptor-related protein 1 (LRP1) regulates lipid and glucose metabolism in liver and adipose tissue. It is also involved in central nervous system regulation of food intake and leptin signalling. Here we demonstrate that endothelial Lrp1 regulates systemic energy homeostasis...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mao, Hua, Lockyer, Pamela, Li, Luge, Ballantyne, Christie M., Patterson, Cam, Xie, Liang, Pi, Xinchun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394236/
https://ncbi.nlm.nih.gov/pubmed/28393867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14960
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