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LRP1 regulates retinal angiogenesis by inhibiting PARP-1 activity and endothelial cell proliferation

OBJECTIVE: We recently demonstrated that low-density lipoprotein receptor related protein 1 (LRP1) is required for cardiovascular development in zebrafish. However, what role LRP1 plays in angiogenesis remains to be determined. To better understand the role of LRP1 in endothelial cell function, we i...

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Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Mao, Hua, Lockyer, Pamela, Townley-Tilson, Davin, Xie, Liang, Pi, Xinchun
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732907/
https://ncbi.nlm.nih.gov/pubmed/26634655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306713
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