An LRP1-Dependent Endocytic Mechanism Governs the Signaling Output of the BMP System in Endothelial Cells and in Angiogenesis

RATIONALE: Among the extracellular modulators of Bmp (bone morphogenetic protein) signaling, Bmper (Bmp endothelial cell precursor-derived regulator) both enhances and inhibits Bmp signaling. Recently we found that Bmper modulates Bmp4 activity via a concentration-dependent, endocytic trap-and-sink...

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Detaylı Bibliyografya
Asıl Yazarlar: Pi, Xinchun, Schmitt, Christopher E., Xie, Liang, Portbury, Andrea L., Wu, Yaxu, Lockyer, Pamela, Dyer, Laura A., Moser, Martin, Bu, Guojun, Flynn, Edward J., Jin, Suk-Won, Patterson, Cam
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495066/
https://ncbi.nlm.nih.gov/pubmed/22777006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.274597
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