Germline Alterations in RASAL1 in Cowden Syndrome Patients Presenting with Follicular Thyroid Cancer and in Individuals with Apparently Sporadic Epithelial Thyroid Cancer

CONTEXT: RASAL1 has recently been identified as an important tumor suppressor for sporadic thyroid tumorigenesis, particularly for follicular thyroid cancer (FTC) and anaplastic thyroid cancer. Thyroid cancer is an important component of Cowden syndrome (CS). Patients with germline PTEN mutations ha...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Ngeow, Joanne, Ni, Ying, Tohme, Rita, Song Chen, Fu, Bebek, Gurkan, Eng, Charis
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
JCEM Online: Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393485/
https://ncbi.nlm.nih.gov/pubmed/24712574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1225
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