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Pigment Epithelium-Derived Factor (PEDF) Suppresses IL-1β-Mediated c-Jun N-Terminal Kinase (JNK) Activation to Improve Hepatocyte Insulin Signaling

Pigment epithelium-derived factor (PEDF) is an antiinflammatory protein that circulates at high levels in the metabolic syndrome. Metabolic studies of PEDF knockout (KO) mice were conducted to investigate the relationship between PEDF, inflammatory markers, and metabolic homeostasis. Male PEDF KO mi...

詳細記述

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書誌詳細
出版年:Endocrinology
主要な著者: Gattu, Arijeet K., Birkenfeld, Andreas L., Iwakiri, Yasuko, Jay, Steven, Saltzman, Mark, Doll, Jennifer, Protiva, Petr, Samuel, Varman T., Crawford, Susan E., Chung, Chuhan
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393334/
https://ncbi.nlm.nih.gov/pubmed/24456163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1785
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