MYO6 is targeted by Salmonella virulence effectors to trigger PI3-kinase signaling and pathogen invasion into host cells

To establish infections, Salmonella injects virulence effectors that hijack the host actin cytoskeleton and phosphoinositide signaling to drive pathogen invasion. How effectors reprogram the cytoskeleton network remains unclear. By reconstituting the activities of the Salmonella effector SopE, we re...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Brooks, Andrew B. E., Humphreys, Daniel, Singh, Vikash, Davidson, Anthony C., Arden, Susan D., Buss, Folma, Koronakis, Vassilis
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393208/
https://ncbi.nlm.nih.gov/pubmed/28348208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616418114
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