MYO6 is targeted by Salmonella virulence effectors to trigger PI3-kinase signaling and pathogen invasion into host cells

To establish infections, Salmonella injects virulence effectors that hijack the host actin cytoskeleton and phosphoinositide signaling to drive pathogen invasion. How effectors reprogram the cytoskeleton network remains unclear. By reconstituting the activities of the Salmonella effector SopE, we re...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Brooks, Andrew B. E., Humphreys, Daniel, Singh, Vikash, Davidson, Anthony C., Arden, Susan D., Buss, Folma, Koronakis, Vassilis
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393208/
https://ncbi.nlm.nih.gov/pubmed/28348208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616418114
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