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ERRα induces H3K9 demethylation by LSD1 to promote cell invasion

Lysine Specific Demethylase 1 (LSD1) removes mono- and dimethyl groups from lysine 4 of histone H3 (H3K4) or H3K9, resulting in repressive or activating (respectively) transcriptional histone marks. The mechanisms that control the balance between these two antagonist activities are not understood. W...

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Publicado en:Proc Natl Acad Sci U S A
Main Authors: Carnesecchi, Julie, Forcet, Christelle, Zhang, Ling, Tribollet, Violaine, Barenton, Bruno, Boudra, Rafik, Cerutti, Catherine, Billas, Isabelle M. L., Sérandour, Aurélien A., Carroll, Jason S., Beaudoin, Claude, Vanacker, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393192/
https://ncbi.nlm.nih.gov/pubmed/28348226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614664114
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