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ERRα protein is stabilized by LSD1 in a demethylation-independent manner

The LSD1 histone demethylase is highly expressed in breast tumors where it constitutes a factor of poor prognosis and promotes traits of cancer aggressiveness such as cell invasiveness. Recent work has shown that the Estrogen-Related Receptor α (ERRα) induces LSD1 to demethylate the Lys 9 of histone...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Carnesecchi, Julie, Cerutti, Catherine, Vanacker, Jean-Marc, Forcet, Christelle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708767/
https://ncbi.nlm.nih.gov/pubmed/29190800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188871
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