LSD1-ERRα complex requires NRF1 to positively regulate transcription and cell invasion

Lysine-specific demethylase 1 (LSD1) exerts dual effects on histone H3, promoting transcriptional repression via Lys4 (H3K4) demethylation or transcriptional activation through Lys9 (H3K9) demethylation. These activities are often exerted at transcriptional start sites (TSSs) and depend on the type...

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Publicado en:Sci Rep
Main Authors: Zhang, Ling, Carnesecchi, Julie, Cerutti, Catherine, Tribollet, Violaine, Périan, Séverine, Forcet, Christelle, Wong, Jiemin, Vanacker, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030097/
https://ncbi.nlm.nih.gov/pubmed/29968728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27676-8
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