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The telomeric DNA damage response occurs in the absence of chromatin decompaction
Telomeres are specialized nucleoprotein structures that protect chromosome ends from DNA damage response (DDR) and DNA rearrangements. The telomeric shelterin protein TRF2 suppresses the DDR, and this function has been attributed to its abilities to trigger t-loop formation or prevent massive decomp...
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| Publicado no: | Genes Dev |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5393052/ https://ncbi.nlm.nih.gov/pubmed/28381410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.294082.116 |
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