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Pyrano[2,3,4-cd]indole as a Scaffold for Selective Nonbasic 5-HT(6)R Ligands
[Image: see text] In this letter, we report the synthesis of a pyrano[2,3,4-cd]indole chemical scaffold designed through a tandem bioisostere generation/virtual screening protocol in search of 5-HT(6)R ligands. The discovered chemical scaffold resulted in the design of highly active basic and nonbas...
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| הוצא לאור ב: | ACS Med Chem Lett |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Chemical
Society
2017
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5392774/ https://ncbi.nlm.nih.gov/pubmed/28435524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00482 |
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