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Bioisosteric Matrices for Ligands of Serotonin Receptors
The concept of bioisosteric replacement matrices is applied to explore the chemical space of serotonin receptor ligands, aiming to determine the most efficient ways of manipulating the affinity for all 5-HT receptor subtypes. Analysis of a collection of over 1 million bioisosteres of compounds with...
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| Publié dans: | ChemMedChem |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
WILEY-VCH Verlag
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4471634/ https://ncbi.nlm.nih.gov/pubmed/25772514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201402563 |
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