From Homology Models to a Set of Predictive Binding Pockets – a 5-HT(1A) Receptor Case Study

Despite its remarkable importance in the arena of drug design, serotonin 1A receptor (5-HT(1A)) has been elusive to the x-ray crystallography community. This lack of direct structural information not only hampers our knowledge regarding the binding modes of many popular ligands (including endogenous...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Chem Inf Model
Prif Awduron: Warszycki, Dawid, Rueda, Manuel, Mordalski, Stefan, Kristiansen, Kurt, Satała, Grzegorz, Rataj, Krzysztof, Chilmonczyk, Zdzisław, Sylte, Ingebrigt, Abagyan, Ruben, Bojarski, Andrzej J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361891/
https://ncbi.nlm.nih.gov/pubmed/28055203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.6b00263
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