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Selenocysteine Insertion at a Predefined UAG Codon in a Release Factor 1 (RF1)-depleted Escherichia coli Host Strain Bypasses Species Barriers in Recombinant Selenoprotein Translation
Selenoproteins contain the amino acid selenocysteine (Sec), co-translationally inserted at a predefined UGA opal codon by means of Sec-specific translation machineries. In Escherichia coli, this process is dependent upon binding of the Sec-dedicated elongation factor SelB to a Sec insertion sequence...
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Izdano u: | J Biol Chem |
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Glavni autori: | , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society for Biochemistry and Molecular Biology
2017
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5392690/ https://ncbi.nlm.nih.gov/pubmed/28193838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.776310 |
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