SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy: SGLT2 PROTEIN INHIBITION DECREASES RENAL LIPID ACCUMULATION, INFLAMMATION, AND THE DEVELOPMENT OF NEPHROPATHY IN DIABETIC MICE

There is very limited human renal sodium gradient-dependent glucose transporter protein (SGLT2) mRNA and protein expression data reported in the literature. The first aim of this study was to determine SGLT2 mRNA and protein levels in human and animal models of diabetic nephropathy. We have found th...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Wang, Xiaoxin X., Levi, Jonathan, Luo, Yuhuan, Myakala, Komuraiah, Herman-Edelstein, Michal, Qiu, Liru, Wang, Dong, Peng, Yingqiong, Grenz, Almut, Lucia, Scott, Dobrinskikh, Evgenia, D'Agati, Vivette D., Koepsell, Hermann, Kopp, Jeffrey B., Rosenberg, Avi Z., Levi, Moshe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2017
Onderwerpen:
Molecular Bases of Disease
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392679/
https://ncbi.nlm.nih.gov/pubmed/28196866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.779520
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