Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT

Peptide antigen presentation by major histocompatibility complex (MHC) class I proteins initiates CD8(+) T cell-mediated immunity against pathogens and cancers. MHC I molecules typically bind peptides with 9 amino acids in length with both ends tucked inside the major A and F binding pockets. It has...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Remesh, Soumya G., Andreatta, Massimo, Ying, Ge, Kaever, Thomas, Nielsen, Morten, McMurtrey, Curtis, Hildebrand, William, Peters, Bjoern, Zajonc, Dirk M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392673/
https://ncbi.nlm.nih.gov/pubmed/28179428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.776542
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