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The length distribution of class I restricted T cell epitopes is determined by both peptide supply and MHC allele specific binding preference
HLA class I binding predictions are widely used to identify candidate peptide targets of human CD8+ T cell responses. Many such approaches focus exclusively on a limited range of peptide lengths, typically 9 and sometimes 9-10 amino acids, despite multiple examples of dominant epitopes of other leng...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4744552/ https://ncbi.nlm.nih.gov/pubmed/26783342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501721 |
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