Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model

Oral supplementation with branched-chain amino acids (BCAA; leucine, isoleucine, and valine) in patients with liver cirrhosis potentially suppresses the incidence of hepatocellular carcinoma (HCC) and improves event-free survival. However, the detailed mechanisms of BCAA action have not been fully e...

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Udgivet i:Oncotarget
Main Authors: Takegoshi, Kai, Honda, Masao, Okada, Hikari, Takabatake, Riuta, Matsuzawa-Nagata, Naoto, Campbell, Jean S., Nishikawa, Masashi, Shimakami, Tetsuro, Shirasaki, Takayoshi, Sakai, Yoshio, Yamashita, Taro, Takamura, Toshinari, Tanaka, Takuji, Kaneko, Shuichi
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392319/
https://ncbi.nlm.nih.gov/pubmed/28212548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15304
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