Mevastatin blockade of autolysosome maturation stimulates LBH589-induced cell death in triple-negative breast cancer cells

Histone deacetylase inhibitors (HDACi) are promising anti-cancer agents, and combining a HDACi with other agents is an attractive therapeutic strategy in solid tumors. We report here that mevastatin increases HDACi LBH589-induced cell death in triple-negative breast cancer (TNBC) cells. Combination...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lin, Zhaohu, Zhang, Zhuqing, Jiang, Xiaoxiao, Kou, Xinhui, Bao, Yong, Liu, Huijuan, Sun, Fanghui, Ling, Shuang, Qin, Ning, Jiang, Lan, Yang, Yonghua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392290/
https://ncbi.nlm.nih.gov/pubmed/28147319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14868
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