The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma

Drug repurposing is currently an important approach for accelerating drug discovery and development for clinical use. Hepatocellular carcinoma (HCC) presents drug resistance to chemotherapy, and the prognosis is poor due to the existence of liver cancer stem-like cells. In this study, we investigate...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Jia-Jie, Cai, Nan, Chen, Guan-Zhong, Jia, Chang-Chang, Qiu, Dong-Bo, Du, Cong, Liu, Wei, Yang, Yang, Long, Zi-Jie, Zhang, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392272/
https://ncbi.nlm.nih.gov/pubmed/26061710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.4307
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