Baculovirus-Mediated miRNA Regulation to Suppress Hepatocellular Carcinoma Tumorigenicity and Metastasis

MicroRNA 122 (miR-122) is a tumor suppressor for hepatocellular carcinoma (HCC) but is lowly expressed in HCC cells. MiR-151 is aberrantly overexpressed in HCC cells and promotes HCC metastasis yet its roles on HCC tumorigenicity are unknown. To combat HCC tumorigenicity/metastasis, we developed Sle...

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Dettagli Bibliografici
Pubblicato in:Mol Ther
Autori principali: Chen, Chiu-Ling, Wu, Jaw-Ching, Chen, Guan-Yu, Yuan, Pei-Hsiang, Tseng, Yen-Wen, Li, Kuei-Chang, Hwang, Shiaw-Min, Hu, Yu-Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426788/
https://ncbi.nlm.nih.gov/pubmed/25023326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.126
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