The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma

Drug repurposing is currently an important approach for accelerating drug discovery and development for clinical use. Hepatocellular carcinoma (HCC) presents drug resistance to chemotherapy, and the prognosis is poor due to the existence of liver cancer stem-like cells. In this study, we investigate...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Chen, Jia-Jie, Cai, Nan, Chen, Guan-Zhong, Jia, Chang-Chang, Qiu, Dong-Bo, Du, Cong, Liu, Wei, Yang, Yang, Long, Zi-Jie, Zhang, Qi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392272/
https://ncbi.nlm.nih.gov/pubmed/26061710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.4307
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