A double-blind, placebo-controlled, pilot study of riluzole monotherapy for acute bipolar depression

BACKGROUND: Glutamatergic system abnormalities are implicated in the pathophysiology and treatment of both major depressive disorder and bipolar depression (BDep). Subsequent to studies demonstrating the rapid and robust antidepressant effects of ketamine, an N-methyl-D-aspartate (NMDA) receptor ant...

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Pubblicato in:J Clin Psychopharmacol
Autori principali: Park, Lawrence T., Lener, Marc S., Luckenbaugh, David A., Hopkins, Matthew, Iadorola, Nicolas, Vieira, Rodrigo Machado, Ballard, Elizabeth, Nugent, Allison, Zarate, Carlos A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392145/
https://ncbi.nlm.nih.gov/pubmed/28338546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JCP.0000000000000693
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