A double-blind, Randomized, Placebo-Controlled 4-Week Study on the Efficacy and Safety of the Purinergic Agents Allopurinol and Dipyridamole Adjunctive to Lithium in Acute Bipolar Mania

OBJECTIVE: The therapeutics for Bipolar Disorders (BD) is still far from adequate and new options with improved effectiveness, safety and tolerability in a wide range of patients are necessary. Preliminary data have suggested a role for dysfunctions targeting at the purinergic system in mood disorde...

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Main Authors: Machado-Vieira, Rodrigo, Soares, Jair C., Lara, Diogo R., Luckenbaugh, David A., Busnello, João V., Marca, Getulio, Cunha, Angelo, Souza, Diogo O., Zarate, Carlos A., Kapczinski, Flavio
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727594/
https://ncbi.nlm.nih.gov/pubmed/18681754
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