SDF-1 is both necessary and sufficient to promote proliferative retinopathy

Diabetic retinopathy is the leading cause of blindness in working-age adults. It is caused by oxygen starvation in the retina inducing aberrant formation of blood vessels that destroy retinal architecture. In humans, vitreal stromal cell–derived factor–1 (SDF-1) concentration increases as proliferat...

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Main Authors: Butler, Jason M., Guthrie, Steven M., Koc, Mehmet, Afzal, Aqeela, Caballero, Sergio, Brooks, H. Logan, Mames, Robert N., Segal, Mark S., Grant, Maria B., Scott, Edward W.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC539202/
https://ncbi.nlm.nih.gov/pubmed/15630447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522869
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