載入...

Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration

FIG4 is a ubiquitously expressed phosphatase that, in complex with FAB1/PIKFYVE and VAC14, regulates the biosynthesis of the signaling lipid PI(3,5)P(2). Null mutation of Fig4 in the mouse results in spongiform degeneration of brain and peripheral ganglia, defective myelination and juvenile lethalit...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Ferguson, C. J., Lenk, G. M., Jones, J. M., Grant, A. E., Winters, J. J., Dowling, J. J., Giger, R. J., Meisler, Miriam H.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406753/
https://ncbi.nlm.nih.gov/pubmed/22581779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds179
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!