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Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS
Oligoclonal IgM bands restricted to cerebrospinal fluid are an unfavorable prognostic marker in MS, the most common demyelinating disease of the CNS. We have attempted to identify the B cell subpopulation responsible for oligoclonal IgM secretion and the specificity of these bands. In addition, we e...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC539201/ https://ncbi.nlm.nih.gov/pubmed/15630459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522833 |
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