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Is the canonical RAF-MEK-ERK signaling pathway a therapeutic target in SCLC?
The activity of the RAF-MEK-ERK signaling pathway is critical for the proliferation of normal and cancerous cells. Oncogenic mutations driving the development of lung adenocarcinoma often activate this signaling pathway. In contrast, pathway activity levels and their biological roles are not well es...
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| Yayımlandı: | J Thorac Oncol |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391975/ https://ncbi.nlm.nih.gov/pubmed/27133774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2016.04.018 |
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