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Interrogating the topological robustness of gene regulatory circuits by randomization

One of the most important roles of cells is performing their cellular tasks properly for survival. Cells usually achieve robust functionality, for example, cell-fate decision-making and signal transduction, through multiple layers of regulation involving many genes. Despite the combinatorial complex...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Autores principales: Huang, Bin, Lu, Mingyang, Jia, Dongya, Ben-Jacob, Eshel, Levine, Herbert, Onuchic, Jose N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391964/
https://ncbi.nlm.nih.gov/pubmed/28362798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005456
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