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Interrogating the topological robustness of gene regulatory circuits by randomization

One of the most important roles of cells is performing their cellular tasks properly for survival. Cells usually achieve robust functionality, for example, cell-fate decision-making and signal transduction, through multiple layers of regulation involving many genes. Despite the combinatorial complex...

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發表在:PLoS Comput Biol
Main Authors: Huang, Bin, Lu, Mingyang, Jia, Dongya, Ben-Jacob, Eshel, Levine, Herbert, Onuchic, Jose N.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391964/
https://ncbi.nlm.nih.gov/pubmed/28362798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005456
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