TUFT1, a novel candidate gene for metatarsophalangeal osteoarthritis, plays a role in chondrogenesis on a calcium-related pathway

Osteoarthritis (OA) is the most common degenerative joint disorder and genetic factors have been shown to have a significant role in its etiology. The first metatarsophalangeal joint (MTP I) is highly susceptible to development of OA due to repetitive mechanical stress during walking. We used whole...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sliz, Eeva, Taipale, Mari, Welling, Maiju, Skarp, Sini, Alaraudanjoki, Viivi, Ignatius, Jaakko, Ruddock, Lloyd, Nissi, Ritva, Männikkö, Minna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391938/
https://ncbi.nlm.nih.gov/pubmed/28410428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175474
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