Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritis

INTRODUCTION: Osteoarthritis (OA) is the most common degenerative joint disease and one of the major causes of disability worldwide. It is a multifactorial disorder with a significant genetic component. The heritability of OA has been estimated to be 60% for hip OA and 39% for knee OA. Genetic facto...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Skarp, Sini, Kämäräinen, Olli-Pekka, Wei, Gong-Hong, Jakkula, Eveliina, Kiviranta, Ilkka, Kröger, Heikki, Auvinen, Juha, Lehenkari, Petri, Ala-Kokko, Leena, Männikkö, Minna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6114922/
https://ncbi.nlm.nih.gov/pubmed/30157244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203313
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